River
Amazon
The Amazon River is the largest river by volume in the world and one of the most biodiverse regions on the planet. Stretching over 4,000 miles through Peru, Colombia, and Brazil, the river winds through the heart of the Amazon Rainforest, a vast and ecologically rich landscape often referred to as the "lungs of the Earth."
An Amazon River cruise offers a rare opportunity to explore remote ecosystems, spot extraordinary wildlife—including pink river dolphins, sloths, toucans, and caimans—and connect with Indigenous cultures living along the riverbanks. Most luxury cruises navigate the Peruvian Amazon, departing from Iquitos and venturing deep into the Pacaya-Samiria National Reserve, a protected area teeming with life.
From sunrise skiff rides and jungle hikes to village visits and canopy walks, Amazon River cruises blend soft adventure with educational enrichment. Ships are typically small and eco-conscious, designed to operate in harmony with the environment while offering comfort and connection in the world’s most awe-inspiring natural setting.
Peru (Upper Amazon)
Iquitos, Peru
As the largest city in the Peruvian Amazon—and one of the few major cities in the world inaccessible by road—Iquitos is the primary gateway for Amazon River cruises in Peru. This vibrant city blends colonial charm with rainforest energy, offering colorful markets, rubber boom architecture, and riverfront culture. Most luxury cruises, including those by Aqua Expeditions and Delfin, begin with a flight into Iquitos, followed by a transfer to the embarkation point.
Nauta, Peru
Located about two hours from Iquitos by road, Nauta is a small riverside town that serves as the launch point for most Upper Amazon itineraries. It offers easy access to the Pacaya-Samiria National Reserve, a vast protected area known for its remarkable biodiversity. Cruises from Nauta often venture deep into rainforest tributaries, where travelers may encounter sloths, macaws, pink dolphins, and remote communities along the riverbanks.
Brazil (Middle and Lower Amazon)
Manaus, Brazil
Manaus is the cultural and economic center of the Brazilian Amazon, as well as one of the most important cruise ports in the region. Known for the striking Amazon Theatre and the natural phenomenon called the Meeting of the Waters, Manaus offers a unique blend of jungle and city. It serves as a departure point for both river cruises and expedition ships heading into the depths of the rainforest or toward the Atlantic coast.
Santarém, Brazil
Situated between Manaus and Belém, Santarém is a charming river port that offers access to one of the Amazon’s hidden gems—Alter do Chão. This nearby village is famed for its white-sand beaches, clear water, and laid-back vibe. Santarém is often featured on longer cruise itineraries, particularly those exploring the Tapajós River, a tributary known for its tranquil beauty and diverse wildlife.
Belém, Brazil
Positioned at the mouth of the Amazon River where it meets the Atlantic Ocean, Belém is a lively port city with strong Portuguese influences. It is a turnaround point for some Lower Amazon itineraries and a fascinating destination in its own right. Belém’s Ver-o-Peso market is one of the largest open-air markets in South America, showcasing Amazonian produce, seafood, and local culture. It’s an ideal starting or ending point for travelers seeking a blend of rainforest access and city exploration.
Colombia (Amazon Trifrontier)
Leticia, Colombia
Located at the intersection of Colombia, Peru, and Brazil, Leticia is a small but culturally rich port town on the Amazon River. Though less developed for cruising, it serves as a base for jungle lodges, wildlife excursions, and regional river journeys. Accessible by air from Bogotá, Leticia offers a more off-the-beaten-path entry into the Amazon, with opportunities to explore Indigenous communities, rainforest trails, and the unique dynamics of the tri-border region.